Cargando…

CO-Induced TTP Activation Alleviates Cellular Senescence and Age-Dependent Hepatic Steatosis via Downregulation of PAI-1

Aging can increase the risk of various hepatic diseases, especially non-alcoholic fatty liver disease (NAFLD). Although the mechanisms underlying the pathogenesis of age-related disorders such as NAFLD remain incompletely understood, recent studies have implicated the accumulation of senescent cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Jeongmin, Chen, Yingqing, Kim, Jeongha, Hwang, Eunyeong, Park, Gyu Hwan, Yang, Chae Ha, Ryter, Stefan W, Park, Jeong Woo, Chung, Hun Taeg, Joe, Yeonsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017156/ https://www.ncbi.nlm.nih.gov/pubmed/37008056 http://dx.doi.org/10.14336/AD.2023.0120

Ejemplares similares

Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis
por: Chen, Yingqing, et al.
Publicado: (2016)

Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism
por: Park, Jeongmin, et al.
Publicado: (2019)

CD38/ADP-ribose/TRPM2-mediated nuclear Ca(2+) signaling is essential for hepatic gluconeogenesis in fasting and diabetes
por: Rah, So-Young, et al.
Publicado: (2023)

FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway
por: Joe, Yeonsoo, et al.
Publicado: (2018)

Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells
por: Pandiri, Indira, et al.
Publicado: (2016)

Carbon monoxide attenuates amyloidogenesis via down‐regulation of NF‐κB‐mediated BACE1 gene expression
por: Kim, Hyo Jeong, et al.
Publicado: (2018)

Pterostilbene 4′-β-Glucoside Protects against DSS-Induced Colitis via Induction of Tristetraprolin
por: Chen, Yingqing, et al.
Publicado: (2017)

Pterostilbene 4′-β-Glucoside Attenuates LPS-Induced Acute Lung Injury via Induction of Heme Oxygenase-1
por: Park, Jeongmin, et al.
Publicado: (2018)

Carbon Monoxide Inhibits Tenascin-C Mediated Inflammation via IL-10 Expression in a Septic Mouse Model
por: Uddin, Md. Jamal, et al.
Publicado: (2015)

Carbon monoxide decreases interleukin-1β levels in the lung through the induction of pyrin
por: Kim, Seul-Ki, et al.
Publicado: (2017)

Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury
por: Kim, Hyo Jeong, et al.
Publicado: (2018)

Role of PAI-1 in hepatic steatosis and dyslipidemia
por: Levine, Joshua A., et al.
Publicado: (2021)

Antagonistic crosstalk between SIRT1, PARP-1, and -2 in the regulation of chronic inflammation associated with aging and metabolic diseases
por: Chung, Hun Taeg, et al.
Publicado: (2014)

Tristetraprolin Mediates Anti-Inflammatory Effect of Carbon Monoxide against DSS-Induced Colitis
por: Joe, Yeonsoo, et al.
Publicado: (2014)

Quercetin Induces Mitochondrial Biogenesis through Activation of HO-1 in HepG2 Cells
por: Rayamajhi, Nabin, et al.
Publicado: (2013)

Carbon Monoxide Protects against Hepatic Ischemia/Reperfusion Injury via ROS-Dependent Akt Signaling and Inhibition of Glycogen Synthase Kinase 3β
por: Kim, Hyo Jeong, et al.
Publicado: (2013)

IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production
por: Jamal Uddin, Md, et al.
Publicado: (2016)

Carbon Monoxide Attenuates Dextran Sulfate Sodium-Induced Colitis via Inhibition of GSK-3β Signaling
por: Uddin, Md. Jamal, et al.
Publicado: (2013)

PERK activation by SB202190 ameliorates amyloidogenesis via the TFEB-induced autophagy-lysosomal pathway
por: Do, Mihyang, et al.
Publicado: (2022)

Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2
por: Irungbam, Karuna, et al.
Publicado: (2019)

Anti-4-1BB antibody-based combination therapy augments antitumor immunity by enhancing CD11c(+)CD8(+) T cells in renal cell carcinoma
por: Ju, Seong-A, et al.
Publicado: (2022)

Stress granules counteract senescence by sequestration of PAI‐1
por: Omer, Amr, et al.
Publicado: (2018)

ADAMTS13, TTP and Beyond
por: Zheng, X Long
Publicado: (2012)

Differential Regulation of Toll-Like Receptor-Mediated Cytokine Production by Unfolded Protein Response
por: Kim, Sena, et al.
Publicado: (2018)

P1612: CALPROTECTIN LEVELS ARE ELEVATED IN CONGENITAL TTP AND IMMUNE TTP AT ADAMTS13 RELAPSE
por: Subhan, Maryam, et al.
Publicado: (2023)

A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence
por: Ghosh, Asish K., et al.
Publicado: (2016)

Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1
por: Kim, Seung Hyeon, et al.
Publicado: (2021)

Potential Role of Heme Oxygenase-1 in the Resolution of Experimentally Induced Colitis through Regulation of Macrophage Polarization
por: Gwak, Shin-Young, et al.
Publicado: (2022)

Hydroxychloroquine, TTP, COVID-19, and SLE
por: Sookaromdee, Pathum, et al.
Publicado: (2021)

Analysis of ROQUIN, Tristetraprolin (TTP), and BDNF/miR-16/TTP regulatory axis in late onset Alzheimer’s disease
por: Asadi, Mohammad Reza, et al.
Publicado: (2022)

Heme Oxygenase-1 as a Novel Metabolic Player
por: Chung, Hun-Taeg, et al.
Publicado: (2013)

Induction of Heme Oxygenase-1 with Hemin Reduces Obesity-Induced Adipose Tissue Inflammation via Adipose Macrophage Phenotype Switching
por: Tu, Thai Hien, et al.
Publicado: (2014)

Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching
por: Kim, Chu-Sook, et al.
Publicado: (2016)

Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy
por: Kwak, Seo Young, et al.
Publicado: (2021)

Multilevel regulation of HIF-1 signaling by TTP
por: Fähling, Michael, et al.
Publicado: (2012)

Ipilimumab-induced thrombotic thrombocytopenic purpura (TTP)
por: King, Jeanelle, et al.
Publicado: (2017)

From TTP to Glomerulonephritis: A Lifetime of Lupus
por: Kharouf, Fadi, et al.
Publicado: (2021)

PB2322: TTP AFTER COVID 19
por: Gagloeva, D., et al.
Publicado: (2022)

Successful Use of Bortezomib in an Adolescent with Refractory TTP
por: Wali, Junaid Ahmad, et al.
Publicado: (2023)

A Reliable TTP-Based Infrastructure with Low Sensor Resource Consumption for the Smart Home Multi-Platform
por: Kang, Jungho, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ginkh79g0oqg47spsq0ovf0f3u