Granulomatosis with Polyangiitis following COVID-19 in an Adolescent

Granulomatosis with polyangiitis (GPA) is a systemic disease that causes vasculitis in various organs. Although the mechanism of pathogenesis remains unclear, infection has been reported to be a causative factor. We herein report a case of GPA that developed following coronavirus disease 2019 (COVID...

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Detalles Bibliográficos
Autores principales: Nakamura, Yume, Okumura, Fumihiko, Nihei, Mayumi, Chubachi, Kei, Sakamoto, Hiroaki, Ishioka, Yoshiko, Makiguchi, Tomonori, Tanaka, Hisashi, Taima, Kageaki, Yajima, Nobuhisa, Kurose, Akira, Tasaka, Sadatomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017231/
https://www.ncbi.nlm.nih.gov/pubmed/36792217
http://dx.doi.org/10.2169/internalmedicine.1109-22
Descripción
Sumario:Granulomatosis with polyangiitis (GPA) is a systemic disease that causes vasculitis in various organs. Although the mechanism of pathogenesis remains unclear, infection has been reported to be a causative factor. We herein report a case of GPA that developed following coronavirus disease 2019 (COVID-19) in an adolescent girl. One month after contracting mild COVID-19, the patient had facial allodynia, a fever, and weight loss and was admitted for multiple nodular shadows on a chest roentgenogram. GPA was diagnosed based on pathological findings of the lung and nasal mucosal biopsies. She received methylprednisolone and rituximab, and her symptoms and radiological findings improved.

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