Concomitant Pancreatic Ductal Adenocarcinoma and Type 1 Autoimmune Pancreatitis: A Potential Issue in the Diagnosis of Carcinoma by Endoscopic Ultrasound-guided Fine-needle Biopsy

We herein report a 64-year-old man with concomitant pancreatic ductal adenocarcinoma (PDAC) and type 1 autoimmune pancreatitis (AIP). An endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) from the pancreatic head mass revealed level 2 histology of AIP and atypical glands. We diagnosed definit...

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Detalles Bibliográficos
Autores principales: Kachi, Kenta, Naitoh, Itaru, Ban, Tesshin, Hayashi, Kazuki, Yoshida, Michihiro, Hori, Yasuki, Natsume, Makoto, Kato, Akihisa, Kito, Yusuke, Saito, Kenta, Matsuo, Yoichi, Kato, Hiroyuki, Naiki-Ito, Aya, Takahashi, Satoru, Notohara, Kenji, Kataoka, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017232/
https://www.ncbi.nlm.nih.gov/pubmed/35831103
http://dx.doi.org/10.2169/internalmedicine.0075-22
Descripción
Sumario:We herein report a 64-year-old man with concomitant pancreatic ductal adenocarcinoma (PDAC) and type 1 autoimmune pancreatitis (AIP). An endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) from the pancreatic head mass revealed level 2 histology of AIP and atypical glands. We diagnosed definitive focal AIP using the clinical diagnostic criteria. Computed tomography revealed that the pancreatic mass had not been reduced by steroid therapy. Surgery was performed after a histological PDAC diagnosis was made via a transpapillary biliary biopsy. The resected specimen revealed PDAC associated with AIP. It is important to consider the cooccurrence of PDAC and AIP even if the histological diagnosis via an EUS-FNB is AIP.

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