Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin

Metaplastic breast cancer (MBC) is characterized by the histological presence of a mixture of epithelial and mesenchymal-like elements. However, MBC responds poorly to chemotherapy. Due to its rarity, there is no well-defined treatment for MBC. Herein, we report the case of a 56-year-old woman who u...

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Autores principales: Hayashino, Kenta, Zaitsu, Junichi, Kuraoka, Kazuya, Hirata, Taizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017233/
https://www.ncbi.nlm.nih.gov/pubmed/35908970
http://dx.doi.org/10.2169/internalmedicine.9380-22
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author Hayashino, Kenta
Zaitsu, Junichi
Kuraoka, Kazuya
Hirata, Taizo
author_facet Hayashino, Kenta
Zaitsu, Junichi
Kuraoka, Kazuya
Hirata, Taizo
author_sort Hayashino, Kenta
collection PubMed
description Metaplastic breast cancer (MBC) is characterized by the histological presence of a mixture of epithelial and mesenchymal-like elements. However, MBC responds poorly to chemotherapy. Due to its rarity, there is no well-defined treatment for MBC. Herein, we report the case of a 56-year-old woman who underwent a mastectomy and was diagnosed with MBC with osseous differentiation classified as pT4N0M1. After the operation, she was treated with adriamycin and cisplatin, which are standard osteosarcoma treatments, resulting in a partial response. However, to determine the proper chemotherapy treatment, knowledge of the metaplastic elements of the tumor is required.
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spelling pubmed-100172332023-03-16 Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin Hayashino, Kenta Zaitsu, Junichi Kuraoka, Kazuya Hirata, Taizo Intern Med Case Report Metaplastic breast cancer (MBC) is characterized by the histological presence of a mixture of epithelial and mesenchymal-like elements. However, MBC responds poorly to chemotherapy. Due to its rarity, there is no well-defined treatment for MBC. Herein, we report the case of a 56-year-old woman who underwent a mastectomy and was diagnosed with MBC with osseous differentiation classified as pT4N0M1. After the operation, she was treated with adriamycin and cisplatin, which are standard osteosarcoma treatments, resulting in a partial response. However, to determine the proper chemotherapy treatment, knowledge of the metaplastic elements of the tumor is required. The Japanese Society of Internal Medicine 2022-07-29 2023-02-15 /pmc/articles/PMC10017233/ /pubmed/35908970 http://dx.doi.org/10.2169/internalmedicine.9380-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hayashino, Kenta
Zaitsu, Junichi
Kuraoka, Kazuya
Hirata, Taizo
Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title_full Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title_fullStr Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title_full_unstemmed Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title_short Metastatic Metaplastic Breast Cancer Successfully Treated with Adriamycin and Cisplatin
title_sort metastatic metaplastic breast cancer successfully treated with adriamycin and cisplatin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017233/
https://www.ncbi.nlm.nih.gov/pubmed/35908970
http://dx.doi.org/10.2169/internalmedicine.9380-22
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AT zaitsujunichi metastaticmetaplasticbreastcancersuccessfullytreatedwithadriamycinandcisplatin
AT kuraokakazuya metastaticmetaplasticbreastcancersuccessfullytreatedwithadriamycinandcisplatin
AT hiratataizo metastaticmetaplasticbreastcancersuccessfullytreatedwithadriamycinandcisplatin

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