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Mitochondrial stress and glycoxidation increase with decreased kidney function

Mitochondrial stress increases the production of fumarate, an intermediate of the Krebs cycle. Fumarate non-enzymatically reacts with the thiol group of cysteine, leading to the production of S-(2-succinyl)cysteine. Here, we quantified the concentration of fumarate, the free form of S-(2-succinyl)cy...

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Detalles Bibliográficos
Autores principales:	Katsuta, Nana, Nagai, Mime, Saruwatari, Kaishi, Nakamura, Michio, Nagai, Ryoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017327/ https://www.ncbi.nlm.nih.gov/pubmed/36936874 http://dx.doi.org/10.3164/jcbn.22-101

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