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Ion channel chameleons: Switching ion selectivity by alternative splicing
Voltage-gated sodium and calcium channels are distinct, evolutionarily related ion channels that achieve remarkable ion selectivity despite sharing an overall similar structure. Classical studies have shown that ion selectivity is determined by specific binding of ions to the channel pore, enabled b...
Autores principales: | Hsu, Allen L., Ben-Johny, Manu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017353/ https://www.ncbi.nlm.nih.gov/pubmed/36707054 http://dx.doi.org/10.1016/j.jbc.2023.102946 |
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