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A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids

A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heter...

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Autores principales: Salhi, Salma, Oueslati, Ibtissem, Ayari, Sabrina, Kamoun, Elyes, Yazidi, Meriem, Chihaoui, Melika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017403/
https://www.ncbi.nlm.nih.gov/pubmed/36937637
http://dx.doi.org/10.1002/ccr3.7085
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author Salhi, Salma
Oueslati, Ibtissem
Ayari, Sabrina
Kamoun, Elyes
Yazidi, Meriem
Chihaoui, Melika
author_facet Salhi, Salma
Oueslati, Ibtissem
Ayari, Sabrina
Kamoun, Elyes
Yazidi, Meriem
Chihaoui, Melika
author_sort Salhi, Salma
collection PubMed
description A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heterogeneous compressive goiter. The patient was treated with levothyroxine, calcium, and alfacalcidol. A total thyroidectomy was not performed because of the hard adhesion to neighboring structures. Histopathological examination of the thyroid biopsy was consistent with the diagnosis of Riedel's thyroiditis (RT). The patient was treated with glucocorticoids. The outcome was marked by the resolution of compressive symptoms and the decrease of the thyroid gland volume. Serum calcium and parathyroid hormone levels reached normal ranges after the discontinuation of vitaminocalcic supplementation. Hypoparathyroidism may be clinically asymptomatic in a patient with RT as in our case. Early administration of glucocorticoids may be effective in reducing the fibrosclerotic process and lead to the recovery of parathyroid dysfunction.
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spelling pubmed-100174032023-03-17 A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids Salhi, Salma Oueslati, Ibtissem Ayari, Sabrina Kamoun, Elyes Yazidi, Meriem Chihaoui, Melika Clin Case Rep Case Report A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heterogeneous compressive goiter. The patient was treated with levothyroxine, calcium, and alfacalcidol. A total thyroidectomy was not performed because of the hard adhesion to neighboring structures. Histopathological examination of the thyroid biopsy was consistent with the diagnosis of Riedel's thyroiditis (RT). The patient was treated with glucocorticoids. The outcome was marked by the resolution of compressive symptoms and the decrease of the thyroid gland volume. Serum calcium and parathyroid hormone levels reached normal ranges after the discontinuation of vitaminocalcic supplementation. Hypoparathyroidism may be clinically asymptomatic in a patient with RT as in our case. Early administration of glucocorticoids may be effective in reducing the fibrosclerotic process and lead to the recovery of parathyroid dysfunction. John Wiley and Sons Inc. 2023-03-15 /pmc/articles/PMC10017403/ /pubmed/36937637 http://dx.doi.org/10.1002/ccr3.7085 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Salhi, Salma
Oueslati, Ibtissem
Ayari, Sabrina
Kamoun, Elyes
Yazidi, Meriem
Chihaoui, Melika
A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title_full A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title_fullStr A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title_full_unstemmed A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title_short A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
title_sort case of reversible hypoparathyroidism in a patient with riedel's thyroiditis treated with glucocorticoids
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017403/
https://www.ncbi.nlm.nih.gov/pubmed/36937637
http://dx.doi.org/10.1002/ccr3.7085
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