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A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids
A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heter...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017403/ https://www.ncbi.nlm.nih.gov/pubmed/36937637 http://dx.doi.org/10.1002/ccr3.7085 |
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author | Salhi, Salma Oueslati, Ibtissem Ayari, Sabrina Kamoun, Elyes Yazidi, Meriem Chihaoui, Melika |
author_facet | Salhi, Salma Oueslati, Ibtissem Ayari, Sabrina Kamoun, Elyes Yazidi, Meriem Chihaoui, Melika |
author_sort | Salhi, Salma |
collection | PubMed |
description | A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heterogeneous compressive goiter. The patient was treated with levothyroxine, calcium, and alfacalcidol. A total thyroidectomy was not performed because of the hard adhesion to neighboring structures. Histopathological examination of the thyroid biopsy was consistent with the diagnosis of Riedel's thyroiditis (RT). The patient was treated with glucocorticoids. The outcome was marked by the resolution of compressive symptoms and the decrease of the thyroid gland volume. Serum calcium and parathyroid hormone levels reached normal ranges after the discontinuation of vitaminocalcic supplementation. Hypoparathyroidism may be clinically asymptomatic in a patient with RT as in our case. Early administration of glucocorticoids may be effective in reducing the fibrosclerotic process and lead to the recovery of parathyroid dysfunction. |
format | Online Article Text |
id | pubmed-10017403 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100174032023-03-17 A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids Salhi, Salma Oueslati, Ibtissem Ayari, Sabrina Kamoun, Elyes Yazidi, Meriem Chihaoui, Melika Clin Case Rep Case Report A 48‐year‐old woman with a history of primary hypothyroidism, presented with compressive symptoms secondary to a rapid enlargement of a preexisting goiter. She had no clinical signs of hypocalcemia. Biological tests revealed hypoparathyroidism. Cervicothoracic computed tomography scan showed a heterogeneous compressive goiter. The patient was treated with levothyroxine, calcium, and alfacalcidol. A total thyroidectomy was not performed because of the hard adhesion to neighboring structures. Histopathological examination of the thyroid biopsy was consistent with the diagnosis of Riedel's thyroiditis (RT). The patient was treated with glucocorticoids. The outcome was marked by the resolution of compressive symptoms and the decrease of the thyroid gland volume. Serum calcium and parathyroid hormone levels reached normal ranges after the discontinuation of vitaminocalcic supplementation. Hypoparathyroidism may be clinically asymptomatic in a patient with RT as in our case. Early administration of glucocorticoids may be effective in reducing the fibrosclerotic process and lead to the recovery of parathyroid dysfunction. John Wiley and Sons Inc. 2023-03-15 /pmc/articles/PMC10017403/ /pubmed/36937637 http://dx.doi.org/10.1002/ccr3.7085 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Salhi, Salma Oueslati, Ibtissem Ayari, Sabrina Kamoun, Elyes Yazidi, Meriem Chihaoui, Melika A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title | A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title_full | A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title_fullStr | A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title_full_unstemmed | A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title_short | A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids |
title_sort | case of reversible hypoparathyroidism in a patient with riedel's thyroiditis treated with glucocorticoids |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017403/ https://www.ncbi.nlm.nih.gov/pubmed/36937637 http://dx.doi.org/10.1002/ccr3.7085 |
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