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Structure of VanS from vancomycin-resistant enterococci: A sensor kinase with weak ATP binding

The VanRS two-component system regulates the resistance phenotype of vancomycin-resistant enterococci. VanS is a sensor histidine kinase that responds to the presence of vancomycin by autophosphorylating and subsequently transferring the phosphoryl group to the response regulator, VanR. The phosphot...

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Detalles Bibliográficos
Autores principales: Grasty, Kimberly C., Guzik, Claudia, D’Lauro, Elizabeth J., Padrick, Shae B., Beld, Joris, Loll, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017428/
https://www.ncbi.nlm.nih.gov/pubmed/36764524
http://dx.doi.org/10.1016/j.jbc.2023.103001