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Excessive rest time during active phase is reliably detected in a mouse model of myotonic dystrophy type 1 using home cage monitoring
Myotonic dystrophy type 1 (DM1) is a dominantly inherited neuromuscular disease caused by the abnormal expansion of CTG-repeats in the 3′-untranslated region of the Dystrophia Myotonica Protein Kinase (DMPK) gene, characterized by multisystemic symptoms including muscle weakness, myotonia, cardio-re...
Autores principales: | Golini, Elisabetta, Rigamonti, Mara, Raspa, Marcello, Scavizzi, Ferdinando, Falcone, Germana, Gourdon, Genevieve, Mandillo, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017452/ https://www.ncbi.nlm.nih.gov/pubmed/36935893 http://dx.doi.org/10.3389/fnbeh.2023.1130055 |
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