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A conjoint analysis of bulk RNA-seq and single-nucleus RNA-seq for revealing the role of ferroptosis and iron metabolism in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive and selective degeneration of motor neurons in the motor cortex of brain and spinal cord. Ferroptosis is a newly discovered form of cell death and reported to mediate selective motor neuron death in the m...

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Detalles Bibliográficos
Autores principales: Fu, Xiujuan, He, Yizi, Xie, Yongzhi, Lu, Zuneng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017473/
https://www.ncbi.nlm.nih.gov/pubmed/36937665
http://dx.doi.org/10.3389/fnins.2023.1113216