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Discovering highly potent antimicrobial peptides with deep generative model HydrAMP
Antimicrobial peptides emerge as compounds that can alleviate the global health hazard of antimicrobial resistance, prompting a need for novel computational approaches to peptide generation. Here, we propose HydrAMP, a conditional variational autoencoder that learns lower-dimensional, continuous rep...
Autores principales: | Szymczak, Paulina, Możejko, Marcin, Grzegorzek, Tomasz, Jurczak, Radosław, Bauer, Marta, Neubauer, Damian, Sikora, Karol, Michalski, Michał, Sroka, Jacek, Setny, Piotr, Kamysz, Wojciech, Szczurek, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017685/ https://www.ncbi.nlm.nih.gov/pubmed/36922490 http://dx.doi.org/10.1038/s41467-023-36994-z |
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