Cargando…

Trabecular bone remodeling in the aging mouse: A micro-multiphysics agent-based in silico model using single-cell mechanomics

Bone remodeling is regulated by the interaction between different cells and tissues across many spatial and temporal scales. Notably, in silico models are regarded as powerful tools to further understand the signaling pathways that regulate this intricate spatial cellular interplay. To this end, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boaretti, Daniele, Marques, Francisco C., Ledoux, Charles, Singh, Amit, Kendall, Jack J., Wehrle, Esther, Kuhn, Gisela A., Bansod, Yogesh D., Schulte, Friederike A., Müller, Ralph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017748/ https://www.ncbi.nlm.nih.gov/pubmed/36937760 http://dx.doi.org/10.3389/fbioe.2023.1091294

Ejemplares similares

Clinical Data for Parametrization of In Silico Bone Models Incorporating Cell-Cytokine Dynamics: A Systematic Review of Literature
por: Ledoux, Charles, et al.
Publicado: (2022)

Mechanostat parameters estimated from time-lapsed in vivo micro-computed tomography data of mechanically driven bone adaptation are logarithmically dependent on loading frequency
por: Marques, Francisco C., et al.
Publicado: (2023)

Mechano-Regulation of Trabecular Bone Adaptation Is Controlled by the Local in vivo Environment and Logarithmically Dependent on Loading Frequency
por: Scheuren, Ariane C., et al.
Publicado: (2020)

Computational Analysis of Bone Remodeling in the Proximal Tibia Under Electrical Stimulation Considering the Piezoelectric Properties
por: Bansod, Yogesh Deepak, et al.
Publicado: (2021)

Musculoskeletal Modeling of the Lumbar Spine to Explore Functional Interactions between Back Muscle Loads and Intervertebral Disk Multiphysics
por: Toumanidou, Themis, et al.
Publicado: (2015)

Corrigendum: Musculoskeletal Modeling of the Lumbar Spine to Explore Functional Interactions between Back Muscle Loads and Intervertebral Disk Multiphysics
por: Toumanidou, Themis, et al.
Publicado: (2015)

Mechanomics: an emerging field between biology and biomechanics
por: Wang, Jiawen, et al.
Publicado: (2014)

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing
por: Chao, Long, et al.
Publicado: (2021)

A 3D in Silico Multi-Tissue Evolution Model Highlights the Relevance of Local Strain Accumulation in Bone Fracture Remodeling
por: Perier-Metz, Camille, et al.
Publicado: (2022)

Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?
por: McGivern, Hannah, et al.
Publicado: (2020)

Effect of High Hydrostatic Pressure on Human Trabecular Bone Regarding Cell Death and Matrix Integrity
por: Waletzko-Hellwig, Janine, et al.
Publicado: (2021)

Influence of porosity on osteogenesis, bone growth and osteointegration in trabecular tantalum scaffolds fabricated by additive manufacturing
por: Jiao, Juyang, et al.
Publicado: (2023)

In vivo evaluation of osseointegration ability of sintered bionic trabecular porous titanium alloy as artificial hip prosthesis
por: Bai, Xiaowei, et al.
Publicado: (2022)

Mitochondrial Membrane Remodeling
por: Yang, Ziyun, et al.
Publicado: (2022)

Peptide-Enriched Silk Fibroin Sponge and Trabecular Titanium Composites to Enhance Bone Ingrowth of Prosthetic Implants in an Ovine Model of Bone Gaps
por: Lovati, Arianna B., et al.
Publicado: (2020)

An in Silico Approach to Reveal the Nanodisc Formulation of Doxorubicin
por: Xu, Daiyun, et al.
Publicado: (2022)

CaSilico: A versatile CRISPR package for in silico CRISPR RNA designing for Cas12, Cas13, and Cas14
por: Asadbeigi, Adnan, et al.
Publicado: (2022)

In vitro Models of Bone Remodelling and Associated Disorders
por: Owen, Robert, et al.
Publicado: (2018)

Use of Customized 3D-Printed Titanium Augment With Tantalum Trabecular Cup for Large Acetabular Bone Defects in Revision Total Hip Arthroplasty: A Midterm Follow-Up Study
por: Kong, Keyu, et al.
Publicado: (2022)

Towards in silico Models of the Inflammatory Response in Bone Fracture Healing
por: Lafuente-Gracia, Laura, et al.
Publicado: (2021)

In Silico Evaluation of Enzymatic Tunnels in the Biotransformation of α-Tocopherol Esters
por: Azevedo, Tamara Stela Mendonça, et al.
Publicado: (2022)

Convection-Enhanced Delivery In Silico Study for Brain Cancer Treatment
por: Lambride, Chryso, et al.
Publicado: (2022)

Closed-loop control of continuous piperacillin delivery: An in silico study
por: Herrero, Pau, et al.
Publicado: (2022)

A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression
por: Dutta-Moscato, Joyeeta, et al.
Publicado: (2014)

Stability of Norwalk Virus Capsid Protein Interfaces Evaluated by in Silico Nanoindentation
por: Boyd, Kevin J., et al.
Publicado: (2015)

Immune and Clinical Features of CD96 Expression in Glioma by in silico Analysis
por: Zhang, Qiang, et al.
Publicado: (2020)

In silico Assessment of Pharmacological Profile of Low Molecular Weight Oligo-Hydroxyalkanoates
por: Roman, Diana Larisa, et al.
Publicado: (2020)

In silico Design of Linear DNA for Robust Cell-Free Gene Expression
por: Chen, Xinjie, et al.
Publicado: (2021)

Host Response to Biomaterials for Cartilage Tissue Engineering: Key to Remodeling
por: Wei, Fu, et al.
Publicado: (2021)

Role of fibroblasts in wound healing and tissue remodeling on Earth and in space
por: Cialdai, Francesca, et al.
Publicado: (2022)

Corrigendum: Immune and Clinical Features of CD96 Expression in Glioma by in silico Analysis
por: Zhang, Qiang, et al.
Publicado: (2020)

Scaffold-Dependent Mechanical and Architectural Cues Guide Osteochondral Defect Healing in silico
por: Tortorici, Martina, et al.
Publicado: (2021)

Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
por: Biedrzycki, Adam Henry, et al.
Publicado: (2022)

An in-silico Investigation Into the Role of Strain and Structure on Vascular Smooth Muscle Cell Growth
por: McGee, Orla M., et al.
Publicado: (2021)

In Silico Biomechanical Evaluation of WE43 Magnesium Plates for Mandibular Fracture Fixation
por: Orassi, Vincenzo, et al.
Publicado: (2022)

Controlling Mesenchyme Tissue Remodeling via Spatial Arrangement of Mechanical Constraints
por: Winston, Tackla S., et al.
Publicado: (2022)

Improvement of the Activity of a Fungal Versatile-Lipase Toward Triglycerides: An in silico Mechanistic Description
por: Payá-Tormo, Lucía, et al.
Publicado: (2019)

Maternal Smoking Induced Cardiovascular Risks in Fetuses: How Can in silico Models Help?
por: Ho, Harvey, et al.
Publicado: (2020)

In silico Proteomic Analysis Provides Insights Into Phylogenomics and Plant Biomass Deconstruction Potentials of the Tremelalles
por: Aliyu, Habibu, et al.
Publicado: (2020)

New Putative Antimicrobial Candidates: In silico Design of Fish-Derived Antibacterial Peptide-Motifs
por: Okella, Hedmon, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_01sodcbvfnhibql2el1qkk2o28