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Polycystic kidney disease 2-like 1 channel contributes to the bitter aftertaste perception of quinine

Bitterness is an important physiological function in the defense responses to avoid toxic foods. The taste receptor 2 family is well known to mediate bitter taste perception in Type II taste cells. Here, we report that the polycystic kidney disease 2-like 1 (PKD2L1) channel is a novel sensor for the...

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Detalles Bibliográficos
Autores principales: Shimizu, Takahiro, Fujii, Takuto, Hanita, Keisuke, Shinozaki, Ryo, Takamura, Yusaku, Suzuki, Yoshiro, Kageyama, Teppei, Kato, Mizuki, Nishijo, Hisao, Tominaga, Makoto, Sakai, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017821/
https://www.ncbi.nlm.nih.gov/pubmed/36922541
http://dx.doi.org/10.1038/s41598-023-31322-3