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Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix

Aggrecan (ACAN) is localized in the intervertebral disc (IVD) in unique compartment-specific patterns where it contributes to the tissue structure and mechanical function together with collagens. The extracellular matrix (ECM) of the IVD undergoes degenerative changes during aging, misuse or trauma,...

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Detalles Bibliográficos
Autores principales:	Empere, Marta, Wang, Xujia, Prein, Carina, Aspberg, Anders, Moser, Markus, Oohashi, Toshitaka, Clausen-Schaumann, Hauke, Aszodi, Attila, Alberton, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017878/ https://www.ncbi.nlm.nih.gov/pubmed/36937743 http://dx.doi.org/10.3389/fbioe.2023.1128587

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