Immunogenic cell death triggered by impaired deubiquitination in multiple myeloma relies on dysregulated type I interferon signaling

INTRODUCTION: Proteasome inhibition is first line therapy in multiple myeloma (MM). The immunological potential of cell death triggered by defects of the ubiquitin-proteasome system (UPS) and subsequent perturbations of protein homeostasis is, however, less well defined. METHODS: In this paper, we a...

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Detalles Bibliográficos
Autores principales: Waad Sadiq, Zeinab, Brioli, Annamaria, Al-Abdulla, Ruba, Çetin, Gonca, Schütt, Jacqueline, Murua Escobar, Hugo, Krüger, Elke, Ebstein, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018035/
https://www.ncbi.nlm.nih.gov/pubmed/36936919
http://dx.doi.org/10.3389/fimmu.2023.982720

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