PERK‐STING‐RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis‐associated encephalopathy

AIMS: Sepsis‐associated encephalopathy (SAE) is a common but serious complication in septic survivors and often causes long‐term cognitive impairments. The role of RIPK3‐participated necroptosis in SAE remains obscured. STING is a key molecule in regulating necroptosis and apoptosis. However, there...

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Detalles Bibliográficos
Autores principales: Xiaofeng, Guo, You, Wu, Qi, Jia, Hongwei, Ma, Zhongmin, Fan, Shiquan, Wang, Lixia, Du, Yuliang, Peng, Zongping, Fang, Xijing, Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018099/
https://www.ncbi.nlm.nih.gov/pubmed/36694328
http://dx.doi.org/10.1111/cns.14095

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