Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes

The transfer of endocytosed cargoes to lysosomes (LYSs) requires HOPS, a multiprotein complex that tethers late endosomes (LEs) to LYSs before fusion. Many proteins interact with HOPS on LEs/LYSs. However, it is not clear whether these HOPS interactors localize to LEs or LYSs or how they participate...

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Detalles Bibliográficos
Autores principales: Schleinitz, Ariane, Pöttgen, Lara-Alina, Keren-Kaplan, Tal, Pu, Jing, Saftig, Paul, Bonifacino, Juan S., Haas, Albert, Jeschke, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018218/
https://www.ncbi.nlm.nih.gov/pubmed/36640308
http://dx.doi.org/10.1016/j.celrep.2022.111969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018218/
https://www.ncbi.nlm.nih.gov/pubmed/36640308
http://dx.doi.org/10.1016/j.celrep.2022.111969

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