Cargando…

Farnesyl diphosphate synthase promotes cell proliferation by regulating gene expression and alternative splicing profiles in HeLa cells

Farnesyl diphosphate synthase (FDPS), an essential enzyme involved in the mevalonate pathway, is implicated in various diseases, including multiple types of cancer. As an RNA-binding protein (RBP), FDPS is also involved in transcriptional and post-transcriptional regulation. However, to the best of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Lijuan, Chen, Zhigang, Chen, Dong, Kan, Bo, He, Yangfang, Cai, Hanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018273/ https://www.ncbi.nlm.nih.gov/pubmed/36936029 http://dx.doi.org/10.3892/ol.2023.13731

Ejemplares similares

Farnesyl Diphosphate Synthase Inhibitors from In Silico Screening
por: Lindert, Steffen, et al.
Publicado: (2013)

Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness
por: Kim, Hee Yeon, et al.
Publicado: (2018)

Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cells
por: Ory, B, et al.
Publicado: (2008)

Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate
por: Gabriel, Heloisa B, et al.
Publicado: (2018)

Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma
por: Abate, Mario, et al.
Publicado: (2017)

Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum
por: Jordão, Fabiana M, et al.
Publicado: (2013)

Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia
por: Gadelha, Ana Paula R., et al.
Publicado: (2020)

Structure Conservation and Differential Expression of Farnesyl Diphosphate Synthase Genes in Euphorbiaceous Plants
por: Guo, Dong, et al.
Publicado: (2015)

Role of Cys73 in the thermostability of farnesyl diphosphate synthase from Geobacillus stearothermophilus
por: Samori, Petrus Yesaya, et al.
Publicado: (2017)

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl
por: Gong, Daoyong, et al.
Publicado: (2022)

Functional characterization and transcriptional activity analysis of Dryopteris fragrans farnesyl diphosphate synthase genes
por: Zhang, Dongrui, et al.
Publicado: (2023)

Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline
por: Jin, Tingting, et al.
Publicado: (2022)

Using Terpene Synthase Plasticity in Catalysis: On the Enzymatic Conversion of Synthetic Farnesyl Diphosphate Analogues
por: Hou, Anwei, et al.
Publicado: (2021)

Biosynthesis of α-Bisabolol by Farnesyl Diphosphate Synthase and α-Bisabolol Synthase and Their Related Transcription Factors in Matricaria recutita L.
por: Tai, Yuling, et al.
Publicado: (2023)

Cloning and Characterization of Farnesyl Diphosphate Synthase Gene Involved in Triterpenoids Biosynthesis from Poria cocos
por: Wang, Jianrong, et al.
Publicado: (2014)

Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
por: Chan, Yueh-Te, et al.
Publicado: (2017)

Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells
por: Tu, Yafang, et al.
Publicado: (2019)

Studies on the Mechanism of Alloimperatorin on the Proliferation and Apoptosis of HeLa Cells
por: Bai, Yingying, et al.
Publicado: (2021)

Bisphosphonate affects the behavioral responses to HCl by disrupting farnesyl diphosphate synthase in mouse taste bud and tongue epithelial cells
por: Oike, Asami, et al.
Publicado: (2022)

Filamin B extensively regulates transcription and alternative splicing, and is associated with apoptosis in HeLa cells
por: Ma, Hai-Rong, et al.
Publicado: (2020)

Concise synthesis of artemisinin from a farnesyl diphosphate analogue
por: Tang, Xiaoping, et al.
Publicado: (2018)

Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments
por: Ha, Nguyen Thi, et al.
Publicado: (2020)

Cytokeratin 18 regulates the transcription and alternative splicing of apoptotic-related genes and pathways in HeLa cells
por: Cheng, Yi, et al.
Publicado: (2019)

CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell
por: Song, Qingling, et al.
Publicado: (2019)

Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum
por: Nuttall, James M., et al.
Publicado: (2012)

Sesquiterpene Synthase‐Catalysed Formation of a New Medium‐Sized Cyclic Terpenoid Ether from Farnesyl Diphosphate Analogues
por: Huynh, Florence, et al.
Publicado: (2018)

A cytosolic bifunctional geranyl/farnesyl diphosphate synthase provides MVA-derived GPP for geraniol biosynthesis in rose flowers
por: Conart, Corentin, et al.
Publicado: (2023)

SERBP1 affects the apoptotic level by regulating the expression and alternative splicing of cellular and metabolic process genes in HeLa cells
por: Zhou, Junjie, et al.
Publicado: (2022)

Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum
por: Fei, Yu, et al.
Publicado: (2019)

SRSF6 regulates alternative splicing of genes involved in DNA damage response and DNA repair in HeLa cells
por: Yang, Xiao, et al.
Publicado: (2020)

Rational design of Lepidoptera-specific insecticidal inhibitors targeting farnesyl diphosphate synthase, a key enzyme of the juvenile hormone biosynthetic pathway
por: Picard, Marie-Ève, et al.
Publicado: (2021)

Reducing farnesyl diphosphate synthase levels activates Vγ9Vδ2 T cells and improves tumor suppression in murine xenograft cancer models
por: Liou, Mei-Ling, et al.
Publicado: (2022)

Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes
por: Pan, Jian-Jung, et al.
Publicado: (2015)

Inhibition of Coenzyme Qs Accumulation in Engineered Escherichia coli by High Concentration of Farnesyl Diphosphate
por: Samoudi, Mojtaba, et al.
Publicado: (2015)

Expression of LGI1 Impairs Proliferation and Survival of HeLa Cells
por: Gabellini, Nadia, et al.
Publicado: (2009)

Cell Cycle-Regulated Protein Abundance Changes in Synchronously Proliferating HeLa Cells Include Regulation of Pre-mRNA Splicing Proteins
por: Lane, Karen R., et al.
Publicado: (2013)

Electrolyte Metabolism in HeLa Cells
por: Wickson-ginzburg, Margaret, et al.
Publicado: (1963)

Editorial: HeLa Cell Sequela
Publicado: (2013)

The fractured genome of HeLa cells
por: Mittelman, David, et al.
Publicado: (2013)

IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells
por: Fiume, Giuseppe, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_itok4std36378u43u0fp6ia8di