DNA methylation entropy is associated with DNA sequence features and developmental epigenetic divergence

Epigenetic information defines tissue identity and is largely inherited in development through DNA methylation. While studied mostly for mean differences, methylation also encodes stochastic change, defined as entropy in information theory. Analyzing allele-specific methylation in 49 human tissue sa...

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Detalles Bibliográficos
Autores principales: Fang, Yuqi, Ji, Zhicheng, Zhou, Weiqiang, Abante, Jordi, Koldobskiy, Michael A, Ji, Hongkai, Feinberg, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018346/
https://www.ncbi.nlm.nih.gov/pubmed/36762477
http://dx.doi.org/10.1093/nar/gkad050

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