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Elucidating the distinct contributions of miR-122 in the HCV life cycle reveals insights into virion assembly

Efficient hepatitis C virus (HCV) RNA accumulation is dependent upon interactions with the human liver-specific microRNA, miR-122. MiR-122 has at least three roles in the HCV life cycle: it acts as an RNA chaperone, or ‘riboswitch’, allowing formation of the viral internal ribosomal entry site; it p...

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Detalles Bibliográficos
Autores principales:	Rheault, Marylin, Cousineau, Sophie E, Fox, Danielle R, Abram, Quinn H, Sagan, Selena M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018354/ https://www.ncbi.nlm.nih.gov/pubmed/36807979 http://dx.doi.org/10.1093/nar/gkad094

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