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HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair

The 53BP1-dependent end-joining pathway plays a critical role in double-strand break (DSB) repair. However, the regulators of 53BP1 in chromatin remain incompletely characterized. In this study, we identified HDGFRP3 (hepatoma-derived growth factor related protein 3) as a 53BP1-interacting protein....

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Samsa, William E, De, Yanyan, Zhang, Fan, Reizes, Ofer, Almasan, Alexandru, Gong, Zihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018360/
https://www.ncbi.nlm.nih.gov/pubmed/36794849
http://dx.doi.org/10.1093/nar/gkad073