Cargando…
The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells
In melanoma and other cancers, invasion, epithelial-to-mesenchymal transition, metastasis and cancer stem cell maintenance are regulated by transcription factors including the Snail family. Slug (Snail2) protein generally supports migration and apoptosis resistance. However, its role in melanoma is...
Autores principales: | Horák, Pavel, Kreisingerová, Kateřina, Réda, Jiri, Ondrušová, Lubica, Balko, Jan, Vachtenheim, Jiri, Žáková, Petra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018456/ https://www.ncbi.nlm.nih.gov/pubmed/36866769 http://dx.doi.org/10.3892/or.2023.8512 |
Ejemplares similares
-
Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy
por: Réda, Jiri, et al.
Publicado: (2018) -
Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells
por: Vlčková, Kateřina, et al.
Publicado: (2018) -
MITF-Independent Pro-Survival Role of BRG1-Containing SWI/SNF Complex in Melanoma Cells
por: Ondrušová, Lubica, et al.
Publicado: (2013) -
Many Distinct Ways Lead to Drug Resistance in BRAF- and NRAS-Mutated Melanomas
por: Vachtenheim, Jiri, et al.
Publicado: (2021) -
Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells
por: Vlčková, K, et al.
Publicado: (2016)