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Effects of various disaccharide adaptations on recombinant IgA1 production in CHO-K1 suspension cells
Immunoglobulin A (IgA) has been showing potential as a new therapeutic antibody. However, recombinant IgA suffers from low yield. Supplementation of the medium is an effective approach to improving the production and quality of recombinant proteins. In this study, we adapted IgA1-producing CHO-K1 su...
Autores principales: | Choa, John Benson D., Sasaki, Tadahiro, Kajiura, Hiroyuki, Ikuta, Kazuyoshi, Fujiyama, Kazuhito, Misaki, Ryo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018586/ https://www.ncbi.nlm.nih.gov/pubmed/37163134 http://dx.doi.org/10.1007/s10616-023-00571-5 |
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