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Disulfide Bridged Nanoparticles of Thiolated Sodium Alginate and Eudragit RS100 for Oral Delivery of Paclitaxel: In Vitro and In Vivo Evaluation

[Image: see text] Most biopharmaceutics classification system (BCS) class IV drugs have limited oral bioavailability due to poor solubility and poorer permeability. This work aims to investigate the possibility of utilizing disulfide bridged nanoparticles to improve BCS IV drug solubility and oral a...

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Detalles Bibliográficos
Autores principales: Khalid, Hafiz Muhammad Bilal, Rasul, Akhtar, Shah, Shahid, Abbas, Ghulam, Mahmood, Abid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018692/
https://www.ncbi.nlm.nih.gov/pubmed/36936332
http://dx.doi.org/10.1021/acsomega.3c00400