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Selenide Heterostructure Nanosheets with Efficient Near-Infrared Photothermal Conversion for Therapy
[Image: see text] Photothermal therapy has been regarded as one of promising ways for tumor treatment. However, nanoagents with highly efficient thermal conversion and good bio-compatibility are still needed to be developed in biomedicine. In this work, we prepared two-dimensional heterostructures w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018708/ https://www.ncbi.nlm.nih.gov/pubmed/36936278 http://dx.doi.org/10.1021/acsomega.2c07964 |
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author | Lian, Yanbang Wang, Congcong Meng, Yu Dong, Junqiang Zhang, Jianbin Xu, Shiqing Bai, Gongxun Gao, Jianbo |
author_facet | Lian, Yanbang Wang, Congcong Meng, Yu Dong, Junqiang Zhang, Jianbin Xu, Shiqing Bai, Gongxun Gao, Jianbo |
author_sort | Lian, Yanbang |
collection | PubMed |
description | [Image: see text] Photothermal therapy has been regarded as one of promising ways for tumor treatment. However, nanoagents with highly efficient thermal conversion and good bio-compatibility are still needed to be developed in biomedicine. In this work, we prepared two-dimensional heterostructures with bismuth selenide and tungsten selenide nanosheets as photothermal nanoagents. Near-infrared photothermal conversion of selenide heterostructure nanosheets can reach up to 40.75% under 808 nm excitation. It is known that selenium is a critical element to human health. More importantly, our experiments with mice show that the heterostructure nanosheets have low toxicity and high biocompatibility both in vitro and in vivo. The nanoagents based on heterostructures can effectively realize photothermal tumor ablation. It is suggested that the developed selenide nanosheets have great potential application in cancer therapy. |
format | Online Article Text |
id | pubmed-10018708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-100187082023-03-17 Selenide Heterostructure Nanosheets with Efficient Near-Infrared Photothermal Conversion for Therapy Lian, Yanbang Wang, Congcong Meng, Yu Dong, Junqiang Zhang, Jianbin Xu, Shiqing Bai, Gongxun Gao, Jianbo ACS Omega [Image: see text] Photothermal therapy has been regarded as one of promising ways for tumor treatment. However, nanoagents with highly efficient thermal conversion and good bio-compatibility are still needed to be developed in biomedicine. In this work, we prepared two-dimensional heterostructures with bismuth selenide and tungsten selenide nanosheets as photothermal nanoagents. Near-infrared photothermal conversion of selenide heterostructure nanosheets can reach up to 40.75% under 808 nm excitation. It is known that selenium is a critical element to human health. More importantly, our experiments with mice show that the heterostructure nanosheets have low toxicity and high biocompatibility both in vitro and in vivo. The nanoagents based on heterostructures can effectively realize photothermal tumor ablation. It is suggested that the developed selenide nanosheets have great potential application in cancer therapy. American Chemical Society 2023-03-03 /pmc/articles/PMC10018708/ /pubmed/36936278 http://dx.doi.org/10.1021/acsomega.2c07964 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Lian, Yanbang Wang, Congcong Meng, Yu Dong, Junqiang Zhang, Jianbin Xu, Shiqing Bai, Gongxun Gao, Jianbo Selenide Heterostructure Nanosheets with Efficient Near-Infrared Photothermal Conversion for Therapy |
title | Selenide Heterostructure Nanosheets with Efficient
Near-Infrared Photothermal Conversion for Therapy |
title_full | Selenide Heterostructure Nanosheets with Efficient
Near-Infrared Photothermal Conversion for Therapy |
title_fullStr | Selenide Heterostructure Nanosheets with Efficient
Near-Infrared Photothermal Conversion for Therapy |
title_full_unstemmed | Selenide Heterostructure Nanosheets with Efficient
Near-Infrared Photothermal Conversion for Therapy |
title_short | Selenide Heterostructure Nanosheets with Efficient
Near-Infrared Photothermal Conversion for Therapy |
title_sort | selenide heterostructure nanosheets with efficient
near-infrared photothermal conversion for therapy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018708/ https://www.ncbi.nlm.nih.gov/pubmed/36936278 http://dx.doi.org/10.1021/acsomega.2c07964 |
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