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Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements
BACKGROUND: In the recent years active surveillance has been introduced for atypical cartilaginous tumours (ACT). This is the first study on the impact of this new treatment approach on patients’ quality-of-life. We evaluated general health-related quality of life (HRQL) in patients diagnosed with e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018839/ https://www.ncbi.nlm.nih.gov/pubmed/36922843 http://dx.doi.org/10.1186/s13018-023-03694-9 |
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author | Deckers, Claudia van Zeijl, Nander T. van Hooff, Miranda L. Veldman-Goossen, Petra I. Schreuder, H. W. Bart Dierselhuis, Edwin F. van der Geest, Ingrid C. M. |
author_facet | Deckers, Claudia van Zeijl, Nander T. van Hooff, Miranda L. Veldman-Goossen, Petra I. Schreuder, H. W. Bart Dierselhuis, Edwin F. van der Geest, Ingrid C. M. |
author_sort | Deckers, Claudia |
collection | PubMed |
description | BACKGROUND: In the recent years active surveillance has been introduced for atypical cartilaginous tumours (ACT). This is the first study on the impact of this new treatment approach on patients’ quality-of-life. We evaluated general health-related quality of life (HRQL) in patients diagnosed with enchondroma or ACT. METHODS: In this prospective study, patients recently diagnosed with enchondroma and ACT of the long bones were asked to participate. Health-related quality of life (HRQL) was assessed at diagnosis and at six month follow-up, using the 36-item Short Form Health Survey (SF-36) and Numeric Pain Rating Scale (NRS). HRQL of the active surveillance group was compared to the Dutch population and a Dutch sample with locoregional cancer. RESULTS: In total, 45 patients were included in the study, of which four patients underwent curettage and cryosurgery, 41 patients were under active surveillance. The HRQL of the active surveillance group seemed lower compared to the Dutch population, but similar to patients suffering locoregional cancers. No comparison between the surgery and the active surveillance group could be made. In the active surveillance group no statistical difference was found between baseline and six months follow-up regarding HRQL and pain during rest and activities. CONCLUSION: Patients diagnosed with non-malignant chondroid tumours have lower HRQL compared to the healthy population. Active surveillance had no adverse effect on patients well-being, after six months active surveillance the HRQL remained unchanged. Interestingly, in our study no impact on mental health was seen, implicating that diagnosed but untreated chondroid tumours do not seem to influence patients anxiety. |
format | Online Article Text |
id | pubmed-10018839 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-100188392023-03-17 Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements Deckers, Claudia van Zeijl, Nander T. van Hooff, Miranda L. Veldman-Goossen, Petra I. Schreuder, H. W. Bart Dierselhuis, Edwin F. van der Geest, Ingrid C. M. J Orthop Surg Res Research Article BACKGROUND: In the recent years active surveillance has been introduced for atypical cartilaginous tumours (ACT). This is the first study on the impact of this new treatment approach on patients’ quality-of-life. We evaluated general health-related quality of life (HRQL) in patients diagnosed with enchondroma or ACT. METHODS: In this prospective study, patients recently diagnosed with enchondroma and ACT of the long bones were asked to participate. Health-related quality of life (HRQL) was assessed at diagnosis and at six month follow-up, using the 36-item Short Form Health Survey (SF-36) and Numeric Pain Rating Scale (NRS). HRQL of the active surveillance group was compared to the Dutch population and a Dutch sample with locoregional cancer. RESULTS: In total, 45 patients were included in the study, of which four patients underwent curettage and cryosurgery, 41 patients were under active surveillance. The HRQL of the active surveillance group seemed lower compared to the Dutch population, but similar to patients suffering locoregional cancers. No comparison between the surgery and the active surveillance group could be made. In the active surveillance group no statistical difference was found between baseline and six months follow-up regarding HRQL and pain during rest and activities. CONCLUSION: Patients diagnosed with non-malignant chondroid tumours have lower HRQL compared to the healthy population. Active surveillance had no adverse effect on patients well-being, after six months active surveillance the HRQL remained unchanged. Interestingly, in our study no impact on mental health was seen, implicating that diagnosed but untreated chondroid tumours do not seem to influence patients anxiety. BioMed Central 2023-03-16 /pmc/articles/PMC10018839/ /pubmed/36922843 http://dx.doi.org/10.1186/s13018-023-03694-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Deckers, Claudia van Zeijl, Nander T. van Hooff, Miranda L. Veldman-Goossen, Petra I. Schreuder, H. W. Bart Dierselhuis, Edwin F. van der Geest, Ingrid C. M. Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title | Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title_full | Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title_fullStr | Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title_full_unstemmed | Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title_short | Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
title_sort | active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018839/ https://www.ncbi.nlm.nih.gov/pubmed/36922843 http://dx.doi.org/10.1186/s13018-023-03694-9 |
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