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Neuroprotective effects of vinpocetine, as a phosphodiesterase 1 inhibitor, on long-term potentiation in a rat model of Alzheimer’s disease

BACKGROUND: Vinpocetine (Vin) is known as a phosphodiesterase 1 inhibitor (PDE1-I) drug with multilateral effects, including antioxidant and anti-inflammatory activity. In this research, we investigated the neuroprotective and therapeutic effects of Vin through hippocampal synaptic plasticity on a r...

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Detalles Bibliográficos
Autores principales: Shekarian, Meysam, Salehi, Iraj, Raoufi, Safoura, Asadbegi, Masoumeh, Kourosh-Arami, Masoumeh, Komaki, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018848/
https://www.ncbi.nlm.nih.gov/pubmed/36927298
http://dx.doi.org/10.1186/s12868-023-00790-8