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Granulocyte-colony stimulating factor does not prevent in vitro cisplatin-induced germ cell reduction in immature human and mouse testis

BACKGROUND: Currently there are no established fertility preservation options for pre-pubertal boys facing cancer treatment. Granulocyte-colony stimulating factor (G-CSF) treatment has been proposed to be chemoprotective against spermatogonial cell loss in an alkylating chemotherapy model of busulfa...

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Detalles Bibliográficos
Autores principales: Matilionyte, Gabriele, Forsyth, Grace, Guo, Jingtao, Rimmer, Michael P., Hermann, Brian P., Anderson, Richard A., Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018904/
https://www.ncbi.nlm.nih.gov/pubmed/36922758
http://dx.doi.org/10.1186/s12885-023-10702-y

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