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Exposure to oxLDL impairs TGF-β activity in human tendon cells

BACKGROUND: Previous studies have shown that patients with hypercholesterolemia experience elevated levels of oxidized LDL (oxLDL), a molecule which triggers inflammation and collagenase activity. In this study we discovered novel mechanistic effects of oxLDL on tendon cells and the mediators regula...

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Detalles Bibliográficos
Autores principales: Mousavizadeh, Rouhollah, Waugh, Charlie M., DeBruin, Erin, McCormack, Robert G., Duronio, Vincent, Scott, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018928/
https://www.ncbi.nlm.nih.gov/pubmed/36927534
http://dx.doi.org/10.1186/s12891-023-06308-x