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Synthesis and biological evaluation of [(131)I]iodocarvedilol as a potential radiopharmaceutical for heart imaging

The optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [(131)I]iodocarvedilol on the concentration of carvedilol, chloramine-T content, pH of the reaction mixture and reaction time was studied in details. Carvedilol was labeled wi...

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Detalles Bibliográficos
Autores principales: Motaleb, M. A., Attalah, K M, Shweeta, H A, Ibrahim, I. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018969/
https://www.ncbi.nlm.nih.gov/pubmed/36922888
http://dx.doi.org/10.1186/s13065-023-00935-0