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Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction

BACKGROUND: Obesity has been identified as a risk factor for acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, the underlying mechanisms remain elusive. This study aimed to investigate the role of fatty acid synthase (FASN) in lipopolysaccharide (LPS)-induced ALI under obesi...

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Detalles Bibliográficos
Autores principales:	Wu, Zhuhua, Zhu, Li, Nie, Xinran, Liu, Yingli, Zhang, Xiaoju, Qi, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018982/ https://www.ncbi.nlm.nih.gov/pubmed/36922854 http://dx.doi.org/10.1186/s12931-023-02382-w

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