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Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by dif...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019027/ https://www.ncbi.nlm.nih.gov/pubmed/36146896 http://dx.doi.org/10.1093/jhered/esac043 |
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author | Escalona, Merly VanCampen, Jake Maurer, Nicholas W Haukness, Marina Okhovat, Mariam Harris, Robert S Watwood, Allison Hartley, Gabrielle A O’Neill, Rachel J Medvedev, Paul Makova, Kateryna D Vollmers, Christopher Carbone, Lucia Green, Richard E |
author_facet | Escalona, Merly VanCampen, Jake Maurer, Nicholas W Haukness, Marina Okhovat, Mariam Harris, Robert S Watwood, Allison Hartley, Gabrielle A O’Neill, Rachel J Medvedev, Paul Makova, Kateryna D Vollmers, Christopher Carbone, Lucia Green, Richard E |
author_sort | Escalona, Merly |
collection | PubMed |
description | The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates. |
format | Online Article Text |
id | pubmed-10019027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-100190272023-03-17 Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) Escalona, Merly VanCampen, Jake Maurer, Nicholas W Haukness, Marina Okhovat, Mariam Harris, Robert S Watwood, Allison Hartley, Gabrielle A O’Neill, Rachel J Medvedev, Paul Makova, Kateryna D Vollmers, Christopher Carbone, Lucia Green, Richard E J Hered Genome Resources The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates. Oxford University Press 2022-09-23 /pmc/articles/PMC10019027/ /pubmed/36146896 http://dx.doi.org/10.1093/jhered/esac043 Text en © The American Genetic Association. 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Genome Resources Escalona, Merly VanCampen, Jake Maurer, Nicholas W Haukness, Marina Okhovat, Mariam Harris, Robert S Watwood, Allison Hartley, Gabrielle A O’Neill, Rachel J Medvedev, Paul Makova, Kateryna D Vollmers, Christopher Carbone, Lucia Green, Richard E Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title | Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title_full | Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title_fullStr | Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title_full_unstemmed | Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title_short | Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) |
title_sort | whole-genome sequence and assembly of the javan gibbon (hylobates moloch) |
topic | Genome Resources |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019027/ https://www.ncbi.nlm.nih.gov/pubmed/36146896 http://dx.doi.org/10.1093/jhered/esac043 |
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