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Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)

The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by dif...

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Autores principales: Escalona, Merly, VanCampen, Jake, Maurer, Nicholas W, Haukness, Marina, Okhovat, Mariam, Harris, Robert S, Watwood, Allison, Hartley, Gabrielle A, O’Neill, Rachel J, Medvedev, Paul, Makova, Kateryna D, Vollmers, Christopher, Carbone, Lucia, Green, Richard E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019027/
https://www.ncbi.nlm.nih.gov/pubmed/36146896
http://dx.doi.org/10.1093/jhered/esac043
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author Escalona, Merly
VanCampen, Jake
Maurer, Nicholas W
Haukness, Marina
Okhovat, Mariam
Harris, Robert S
Watwood, Allison
Hartley, Gabrielle A
O’Neill, Rachel J
Medvedev, Paul
Makova, Kateryna D
Vollmers, Christopher
Carbone, Lucia
Green, Richard E
author_facet Escalona, Merly
VanCampen, Jake
Maurer, Nicholas W
Haukness, Marina
Okhovat, Mariam
Harris, Robert S
Watwood, Allison
Hartley, Gabrielle A
O’Neill, Rachel J
Medvedev, Paul
Makova, Kateryna D
Vollmers, Christopher
Carbone, Lucia
Green, Richard E
author_sort Escalona, Merly
collection PubMed
description The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
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spelling pubmed-100190272023-03-17 Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch) Escalona, Merly VanCampen, Jake Maurer, Nicholas W Haukness, Marina Okhovat, Mariam Harris, Robert S Watwood, Allison Hartley, Gabrielle A O’Neill, Rachel J Medvedev, Paul Makova, Kateryna D Vollmers, Christopher Carbone, Lucia Green, Richard E J Hered Genome Resources The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates. Oxford University Press 2022-09-23 /pmc/articles/PMC10019027/ /pubmed/36146896 http://dx.doi.org/10.1093/jhered/esac043 Text en © The American Genetic Association. 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Genome Resources
Escalona, Merly
VanCampen, Jake
Maurer, Nicholas W
Haukness, Marina
Okhovat, Mariam
Harris, Robert S
Watwood, Allison
Hartley, Gabrielle A
O’Neill, Rachel J
Medvedev, Paul
Makova, Kateryna D
Vollmers, Christopher
Carbone, Lucia
Green, Richard E
Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title_full Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title_fullStr Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title_full_unstemmed Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title_short Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
title_sort whole-genome sequence and assembly of the javan gibbon (hylobates moloch)
topic Genome Resources
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019027/
https://www.ncbi.nlm.nih.gov/pubmed/36146896
http://dx.doi.org/10.1093/jhered/esac043
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