Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000

Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global Neisseria gonorrhoeae strains has been shown. We present the complete reference genome of the zo...

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Detalles Bibliográficos
Autores principales: Golparian, Daniel, Jacobsson, Susanne, Ohnishi, Makoto, Unemo, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019152/
https://www.ncbi.nlm.nih.gov/pubmed/36853044
http://dx.doi.org/10.1128/mra.01130-22
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author Golparian, Daniel
Jacobsson, Susanne
Ohnishi, Makoto
Unemo, Magnus
author_facet Golparian, Daniel
Jacobsson, Susanne
Ohnishi, Makoto
Unemo, Magnus
author_sort Golparian, Daniel
collection PubMed
description Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global Neisseria gonorrhoeae strains has been shown. We present the complete reference genome of the zoliflodacin-resistant strain H035, which was identified in Japan in 2000.
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spelling pubmed-100191522023-03-17 Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000 Golparian, Daniel Jacobsson, Susanne Ohnishi, Makoto Unemo, Magnus Microbiol Resour Announc Genome Sequences Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global Neisseria gonorrhoeae strains has been shown. We present the complete reference genome of the zoliflodacin-resistant strain H035, which was identified in Japan in 2000. American Society for Microbiology 2023-02-28 /pmc/articles/PMC10019152/ /pubmed/36853044 http://dx.doi.org/10.1128/mra.01130-22 Text en Copyright © 2023 Golparian et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Golparian, Daniel
Jacobsson, Susanne
Ohnishi, Makoto
Unemo, Magnus
Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title_full Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title_fullStr Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title_full_unstemmed Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title_short Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
title_sort complete reference genome sequence of the clinical neisseria gonorrhoeae strain h035, with resistance to the novel antimicrobial zoliflodacin, identified in japan in 2000
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019152/
https://www.ncbi.nlm.nih.gov/pubmed/36853044
http://dx.doi.org/10.1128/mra.01130-22
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