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Evaluation of Oral Tebipenem as a Step-Down Therapy following Intravenous Ertapenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow-Fiber In Vitro Infection Model

Tebipenem is an orally bioavailable carbapenem in development for the treatment of patients with complicated urinary tract infections. Herein, we describe the results of studies designed to evaluate tebipenem’s potential as an oral (p.o.) transition therapy from intravenous (i.v.) ertapenem therapy...

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Detalles Bibliográficos
Autores principales: VanScoy, B. D., Jones, S., Conde, H., Friedrich, L. V., Cotroneo, N., Bhavnani, S. M., Ambrose, P. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019163/
https://www.ncbi.nlm.nih.gov/pubmed/36757190
http://dx.doi.org/10.1128/aac.00908-22