Bioinformatics approaches to analyzing CRISPR screen data: from dropout screens to single-cell CRISPR screens

BACKGROUND: Pooled CRISPR screen is a promising tool in drug targets or essential genes identification with the utilization of three different systems including CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa). Aside from continuous improvements in technology...

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Detalles Bibliográficos
Autores principales: Zhao, Yueshan, Zhang, Min, Yang, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019185/
https://www.ncbi.nlm.nih.gov/pubmed/36937794

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