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Programmable macromolecule-based RNA-targeting therapies to treat human neurological disorders
Disruptions in RNA processing play critical roles in the pathogenesis of neurological diseases. In this Perspective, we discuss recent progress in the development of RNA-targeting therapeutic modalities. We focus on progress, limitations, and opportunities in a new generation of therapies engineered...
Autores principales: | Morelli, Kathryn H., Smargon, Aaron A., Yeo, Gene W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019361/ https://www.ncbi.nlm.nih.gov/pubmed/36693761 http://dx.doi.org/10.1261/rna.079519.122 |
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