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Unlocking the potential of chemically modified peptide nucleic acids for RNA-based therapeutics
RNA therapeutics have emerged as next-generation therapy for the treatment of many diseases. Unlike small molecules, RNA targeted drugs are not limited by the availability of binding pockets on the protein, but rather utilize Watson–Crick (WC) base-pairing rules to recognize the target RNA and modul...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019372/ https://www.ncbi.nlm.nih.gov/pubmed/36653113 http://dx.doi.org/10.1261/rna.079498.122 |