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Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association
Hepatic encephalopathy is the most common neurologic complication of liver cirrhosis, whereas acquired hepatocerebral degeneration (AHD) is an underappreciated neurologic manifestation. Parkinsonism, ataxia, and neuropsychiatric symptoms are its defining characteristics. In individuals with chronic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019375/ https://www.ncbi.nlm.nih.gov/pubmed/36938289 http://dx.doi.org/10.7759/cureus.34968 |
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author | Dubey, Apurva Kumar, Sunil Acharya, Sourya Nagendra, Vadlamudi Khurana, Kashish |
author_facet | Dubey, Apurva Kumar, Sunil Acharya, Sourya Nagendra, Vadlamudi Khurana, Kashish |
author_sort | Dubey, Apurva |
collection | PubMed |
description | Hepatic encephalopathy is the most common neurologic complication of liver cirrhosis, whereas acquired hepatocerebral degeneration (AHD) is an underappreciated neurologic manifestation. Parkinsonism, ataxia, and neuropsychiatric symptoms are its defining characteristics. In individuals with chronic parenchymal liver disease with portosystemic shunting, it is an underrecognized etiology of psychomotor retardation. It has been hypothesized that the etiology of AHD is due to manganese buildup in the basal ganglia. This case report details a hepatocerebral degeneration (AHD) case in a patient with chronic parenchymal liver disease who improved after taking a dopamine agonist. |
format | Online Article Text |
id | pubmed-10019375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-100193752023-03-17 Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association Dubey, Apurva Kumar, Sunil Acharya, Sourya Nagendra, Vadlamudi Khurana, Kashish Cureus Internal Medicine Hepatic encephalopathy is the most common neurologic complication of liver cirrhosis, whereas acquired hepatocerebral degeneration (AHD) is an underappreciated neurologic manifestation. Parkinsonism, ataxia, and neuropsychiatric symptoms are its defining characteristics. In individuals with chronic parenchymal liver disease with portosystemic shunting, it is an underrecognized etiology of psychomotor retardation. It has been hypothesized that the etiology of AHD is due to manganese buildup in the basal ganglia. This case report details a hepatocerebral degeneration (AHD) case in a patient with chronic parenchymal liver disease who improved after taking a dopamine agonist. Cureus 2023-02-14 /pmc/articles/PMC10019375/ /pubmed/36938289 http://dx.doi.org/10.7759/cureus.34968 Text en Copyright © 2023, Dubey et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Dubey, Apurva Kumar, Sunil Acharya, Sourya Nagendra, Vadlamudi Khurana, Kashish Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title | Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title_full | Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title_fullStr | Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title_full_unstemmed | Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title_short | Acquired Parkinson’s Disease in Alcoholic Cirrhosis: The Rarest Association |
title_sort | acquired parkinson’s disease in alcoholic cirrhosis: the rarest association |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019375/ https://www.ncbi.nlm.nih.gov/pubmed/36938289 http://dx.doi.org/10.7759/cureus.34968 |
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