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A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule

BACKGROUNDS AND AIMS: Complete and consecutive observation of the gastrointestinal (GI) tract continues to present challenges for current endoscopy systems. We developed a novel upper and mid gastrointestinal (UMGI) capsule endoscopy using the modified detachable string magnetically controlled capsu...

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Autores principales: Jiang, Bin, Qian, Yang-Yang, Wang, Yuan-Chen, Pan, Jun, Jiang, Xi, Zhu, Jia-Hui, Qiu, Xiao-Ou, Zhou, Wei, Li, Zhao-Shen, Liao, Zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019395/
https://www.ncbi.nlm.nih.gov/pubmed/36927462
http://dx.doi.org/10.1186/s12876-023-02696-5
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author Jiang, Bin
Qian, Yang-Yang
Wang, Yuan-Chen
Pan, Jun
Jiang, Xi
Zhu, Jia-Hui
Qiu, Xiao-Ou
Zhou, Wei
Li, Zhao-Shen
Liao, Zhuan
author_facet Jiang, Bin
Qian, Yang-Yang
Wang, Yuan-Chen
Pan, Jun
Jiang, Xi
Zhu, Jia-Hui
Qiu, Xiao-Ou
Zhou, Wei
Li, Zhao-Shen
Liao, Zhuan
author_sort Jiang, Bin
collection PubMed
description BACKGROUNDS AND AIMS: Complete and consecutive observation of the gastrointestinal (GI) tract continues to present challenges for current endoscopy systems. We developed a novel upper and mid gastrointestinal (UMGI) capsule endoscopy using the modified detachable string magnetically controlled capsule endoscopy (DS-MCE) and inspection method and aimed to assess the clinical application. METHODS: Patients were recruited to undergo UMGI capsule endoscopy followed by esophagogastroduodenoscopy. All capsule procedures in the upper gastrointestinal (UGI) tract were conducted under the control of magnet and string. The main outcome was technical success, and the secondary outcomes included visualization of the UMGI tract, examination time, diagnostic yield, compliance, and safety evaluation. RESULTS: Thirty patients were enrolled and all UMGI capsule procedures realized repeated observation of the esophagus and duodenum with detection rates of 100.0%, 80.0%, and 86.7% of Z-line, duodenal papilla, and reverse side of pylorus, respectively. String detachment was succeeded in 29 patients (96.7%) and the complete examination rate of UMGI tract was 95.45% (21/22). All UMGI capsule procedures were well tolerated with low discomfort score, and had a good diagnostic yield with per-lesion sensitivity of 96.2% in UGI diseases. No adverse events occurred. CONCLUSIONS: This new capsule endoscopy system provides an alternative screening modality for the UMGI tract, and might be indicated in cases of suspected upper and small bowel GI bleeding. Trial registration DS-MCE-UGI and SB, NCT04329468. Registered 27 March 2020, https://clinicaltrials.gov/ct2/results?cond=&term=NCT04329468.
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spelling pubmed-100193952023-03-16 A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule Jiang, Bin Qian, Yang-Yang Wang, Yuan-Chen Pan, Jun Jiang, Xi Zhu, Jia-Hui Qiu, Xiao-Ou Zhou, Wei Li, Zhao-Shen Liao, Zhuan BMC Gastroenterol Research Article BACKGROUNDS AND AIMS: Complete and consecutive observation of the gastrointestinal (GI) tract continues to present challenges for current endoscopy systems. We developed a novel upper and mid gastrointestinal (UMGI) capsule endoscopy using the modified detachable string magnetically controlled capsule endoscopy (DS-MCE) and inspection method and aimed to assess the clinical application. METHODS: Patients were recruited to undergo UMGI capsule endoscopy followed by esophagogastroduodenoscopy. All capsule procedures in the upper gastrointestinal (UGI) tract were conducted under the control of magnet and string. The main outcome was technical success, and the secondary outcomes included visualization of the UMGI tract, examination time, diagnostic yield, compliance, and safety evaluation. RESULTS: Thirty patients were enrolled and all UMGI capsule procedures realized repeated observation of the esophagus and duodenum with detection rates of 100.0%, 80.0%, and 86.7% of Z-line, duodenal papilla, and reverse side of pylorus, respectively. String detachment was succeeded in 29 patients (96.7%) and the complete examination rate of UMGI tract was 95.45% (21/22). All UMGI capsule procedures were well tolerated with low discomfort score, and had a good diagnostic yield with per-lesion sensitivity of 96.2% in UGI diseases. No adverse events occurred. CONCLUSIONS: This new capsule endoscopy system provides an alternative screening modality for the UMGI tract, and might be indicated in cases of suspected upper and small bowel GI bleeding. Trial registration DS-MCE-UGI and SB, NCT04329468. Registered 27 March 2020, https://clinicaltrials.gov/ct2/results?cond=&term=NCT04329468. BioMed Central 2023-03-16 /pmc/articles/PMC10019395/ /pubmed/36927462 http://dx.doi.org/10.1186/s12876-023-02696-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Jiang, Bin
Qian, Yang-Yang
Wang, Yuan-Chen
Pan, Jun
Jiang, Xi
Zhu, Jia-Hui
Qiu, Xiao-Ou
Zhou, Wei
Li, Zhao-Shen
Liao, Zhuan
A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title_full A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title_fullStr A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title_full_unstemmed A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title_short A novel capsule endoscopy for upper and mid-GI tract: the UMGI capsule
title_sort novel capsule endoscopy for upper and mid-gi tract: the umgi capsule
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019395/
https://www.ncbi.nlm.nih.gov/pubmed/36927462
http://dx.doi.org/10.1186/s12876-023-02696-5
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