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Directed evolution of angiotensin‐converting enzyme 2 peptidase activity profiles for therapeutic applications
Angiotensin‐converting enzyme 2 (ACE2) has been investigated for its ability to beneficially modulate the angiotensin receptor (ATR) therapeutic axis to treat multiple human diseases. Its broad substrate scope and diverse physiological roles, however, limit its potential as a therapeutic agent. In t...
Autores principales: | Heinzelman, Pete, Romero, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019445/ https://www.ncbi.nlm.nih.gov/pubmed/36794431 http://dx.doi.org/10.1002/pro.4597 |
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