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Directed evolution of angiotensin‐converting enzyme 2 peptidase activity profiles for therapeutic applications

Angiotensin‐converting enzyme 2 (ACE2) has been investigated for its ability to beneficially modulate the angiotensin receptor (ATR) therapeutic axis to treat multiple human diseases. Its broad substrate scope and diverse physiological roles, however, limit its potential as a therapeutic agent. In t...

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Detalles Bibliográficos
Autores principales: Heinzelman, Pete, Romero, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019445/
https://www.ncbi.nlm.nih.gov/pubmed/36794431
http://dx.doi.org/10.1002/pro.4597

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