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A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates

Mitochondrial depolarization can initiate reversal activity of ATP synthase, depleting ATP by its hydrolysis. We have recently shown that increased ATP hydrolysis contributes to ATP depletion leading to a maladaptation in mitochondrial disorders, where maximal hydrolytic capacity per CV content is i...

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Detalles Bibliográficos
Autores principales: Fernandez-del-Rio, Lucia, Benincá, Cristiane, Villalobos, Frankie, Shu, Cynthia, Stiles, Linsey, Liesa, Marc, Divakaruni, Ajit S, Acin-Perez, Rebeca, Shirihai, Orian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019470/
https://www.ncbi.nlm.nih.gov/pubmed/36918278
http://dx.doi.org/10.26508/lsa.202201628