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Identification of exceptionally potent adenosine deaminases RNA editors from high body temperature organisms

The most abundant form of RNA editing in metazoa is the deamination of adenosines into inosines (A-to-I), catalyzed by ADAR enzymes. Inosines are read as guanosines by the translation machinery, and thus A-to-I may lead to protein recoding. The ability of ADARs to recode at the mRNA level makes them...

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Detalles Bibliográficos
Autores principales: Avram-Shperling, Adi, Kopel, Eli, Twersky, Itamar, Gabay, Orshay, Ben-David, Amit, Karako-Lampert, Sarit, Rosenthal, Joshua J. C., Levanon, Erez Y., Eisenberg, Eli, Ben-Aroya, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019624/
https://www.ncbi.nlm.nih.gov/pubmed/36877730
http://dx.doi.org/10.1371/journal.pgen.1010661