Cargando…

Development of an ectopic huLiver model for Plasmodium liver stage infection

Early Plasmodium falciparum and P. vivax infection requires parasite replication within host hepatocytes, referred to as liver stage (LS). However, limited understanding of infection dynamics in human LS exists due to species-specificity challenges. Reported here is a reproducible, easy-to-manipulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Samayoa-Reyes, Gabriela, Flaherty, Siobhan M., Wickham, Kristina S., Viera-Morilla, Sara, Strauch, Pamela M., Roth, Alison, Padrón, Laura, Jackson, Conner M., Meireles, Patricia, Calvo, David, Roobsoong, Wanlapa, Kangwanrangsan, Niwat, Sattabongkot, Jetsumon, Reichard, Gregory, Lafuente-Monasterio, Maria José, Rochford, Rosemary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019673/ https://www.ncbi.nlm.nih.gov/pubmed/36928885 http://dx.doi.org/10.1371/journal.pone.0279144

Ejemplares similares

Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
por: Flannery, Erika L., et al.
Publicado: (2022)

Overexpression of hepatocyte EphA2 enhances liver-stage infection by Plasmodium vivax
por: Chainarin, Sittinont, et al.
Publicado: (2022)

The challenges of Plasmodium vivax human malaria infection models for vaccine development
por: Roobsoong, Wanlapa, et al.
Publicado: (2023)

A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection
por: Schäfer, Carola, et al.
Publicado: (2020)

Efficient synchronization of Plasmodium knowlesi in vitro cultures using guanidine hydrochloride
por: Ngernna, Sutharinee, et al.
Publicado: (2019)

The Blood Stage Antigen RBP2-P1 of Plasmodium vivax Binds Reticulocytes and Is a Target of Naturally Acquired Immunity
por: Chim-Ong, Anongruk, et al.
Publicado: (2020)

Identification of a PH domain-containing protein which is localized to crystalloid bodies of Plasmodium ookinetes
por: Jenwithisuk, Rachaneeporn, et al.
Publicado: (2018)

Improvement of culture conditions for long-term in vitro culture of Plasmodium vivax
por: Roobsoong, Wanlapa, et al.
Publicado: (2015)

The Plasmodium liver-specific protein 2 (LISP2) is an early marker of liver stage development
por: Gupta, Devendra Kumar, et al.
Publicado: (2019)

A rapid sensitive, flow cytometry-based method for the detection of Plasmodium vivax-infected blood cells
por: Roobsoong, Wanlapa, et al.
Publicado: (2014)

Gene Models, Expression Repertoire, and Immune Response of Plasmodium vivax Reticulocyte Binding Proteins
por: Hietanen, Jenni, et al.
Publicado: (2016)

Transmission efficiency of Plasmodium vivax at low parasitaemia
por: Surit, Thitiporn, et al.
Publicado: (2023)

Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts
por: Rodríguez-Hernández, Diego, et al.
Publicado: (2023)

Prevalence of G6PD deficiency and diagnostic accuracy of a G6PD point-of-care test among a population at risk of malaria in Myanmar
por: Aung, Than Htike, et al.
Publicado: (2023)

Validation of PfSNP-LAMP-Lateral Flow Dipstick for Detection of Single Nucleotide Polymorphism Associated with Pyrimethamine Resistance in Plasmodium falciparum
por: Yongkiettrakul, Suganya, et al.
Publicado: (2020)

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development
por: Zanghi, Gigliola, et al.
Publicado: (2023)

A glance of the blood stage transcriptome of a Southeast Asian Plasmodium ovale isolate
por: Brashear, Awtum M., et al.
Publicado: (2019)

Community acceptability, participation, and adherence to mass drug administration with primaquine for Plasmodium vivax elimination in Southern Thailand: a mixed methods approach
por: Saita, Sayambhu, et al.
Publicado: (2023)

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages
por: Schafer, Carola, et al.
Publicado: (2018)

Case Report: Case Series of Human Plasmodium knowlesi Infection on the Southern Border of Thailand
por: Ngernna, Sutharinee, et al.
Publicado: (2019)

Evaluation of two Plasmodium vivax sexual stage antigens as transmission-blocking vaccine candidates
por: Zhang, Yongzhe, et al.
Publicado: (2021)

Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections
por: Gualdrón-López, Melisa, et al.
Publicado: (2022)

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice
por: Gualdrón-López, Melisa, et al.
Publicado: (2018)

Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model
por: Flaherty, Siobhan, et al.
Publicado: (2022)

Evidence for Aerosol Transfer of SARS-CoV-2–Specific Humoral Immunity
por: Kedl, Ross M., et al.
Publicado: (2023)

Advancing Key Gaps in the Knowledge of Plasmodium vivax Cryptic Infections Using Humanized Mouse Models and Organs-on-Chips
por: Aparici Herraiz, Iris, et al.
Publicado: (2022)

Variation in terpenoids in leaves of Artemisia annua grown under different LED spectra resulting in diverse antimalarial activities against Plasmodium falciparum
por: Sankhuan, Darunmas, et al.
Publicado: (2022)

Climate Change and Malaria Transmission in Thailand
por: Prachumsri, Jetsumon Sattabongkot
Publicado: (2011)

Heat Stress-Responsive Transcriptome Analysis in the Liver Tissue of Hu Sheep
por: Li, Yaokun, et al.
Publicado: (2019)

A member of the CPW-WPC protein family is expressed in and localized to the surface of developing ookinetes
por: Kangwanrangsan, Niwat, et al.
Publicado: (2013)

Characterization of the Plasmodium vivax erythrocytic stage proteome and identification of a potent immunogenic antigen of the asexual stages
por: Roobsoong, Wanlapa, et al.
Publicado: (2010)

Analysis of liver miRNA in Hu sheep with different residual feed intake
por: Lin, Changchun, et al.
Publicado: (2023)

Multidisciplinary Investigations of Sustained Malaria Transmission in the Greater Mekong Subregion
por: Cui, Liwang, et al.
Publicado: (2022)

Maternal HIV Infection as a Risk Factor for Primary Epstein-Barr Virus Infection in Kenyan Infants
por: Samayoa-Reyes, Gabriela, et al.
Publicado: (2022)

IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children
por: Samayoa-Reyes, Gabriela, et al.
Publicado: (2021)

First characterization of Plasmodium vivax liver stage antigen (PvLSA) using synthetic peptides
por: Goo, Youn-Kyoung, et al.
Publicado: (2014)

A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax
por: Pewkliang, Yongyut, et al.
Publicado: (2018)

Natural infection of Plasmodium falciparum induces inhibitory antibodies to gametocyte development in human hosts
por: Tonwong, Natda, et al.
Publicado: (2010)

FLUID PHASE DESTRUCTION OF C2(hu) BY C1(hu) : II. UNMASKING BY C4i(hu)OF C1(hu) SPECIFICITY FOR C2(hu)
por: Gigli, Irma, et al.
Publicado: (1969)

Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN
por: Tian, Mi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2qidnvha4d6dcnhfilub3o275u