Using cultured canine cardiac slices to model the autophagic flux with doxorubicin

Chemotherapy-induced impairment of autophagy is implicated in cardiac toxicity induced by anti-cancer drugs. Imperfect translation from rodent models and lack of in vitro models of toxicity has limited investigation of autophagic flux dysregulation, preventing design of novel cardioprotective strate...

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Detalles Bibliográficos
Autores principales: Boukhalfa, Asma, Robinson, Sally R., Meola, Dawn M., Robinson, Nicholas A., Ling, Lauren A., LaMastro, Joey N., Upshaw, Jenica N., Pulakat, Lakshmi, Jaffe, Iris Z., London, Cheryl A., Chen, Howard H., Yang, Vicky K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019679/
https://www.ncbi.nlm.nih.gov/pubmed/36928870
http://dx.doi.org/10.1371/journal.pone.0282859

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