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RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer
The invasiveness of pancreatic cancer and its resistance to anticancer drugs define its malignant potential, and are considered to affect the peritumoral microenvironment. Cancer cells with resistance to gemcitabine exposed to external signals induced by anticancer drugs may enhance their malignant...
Autores principales: | Ono, Hiroaki, Murase, Yoshiki, Yamashita, Hironari, Kato, Tomotaka, Asano, Daisuke, Ishikawa, Yoshiya, Watanabe, Shuichi, Ueda, Hiroki, Akahoshi, Keiichi, Ogawa, Kosuke, Kudo, Atsushi, Akiyama, Yoshimitsu, Tanaka, Shinji, Tanabe, Minoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019754/ https://www.ncbi.nlm.nih.gov/pubmed/36866763 http://dx.doi.org/10.3892/ijo.2023.5499 |
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