Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex

Identification and characterisation of novel targets for treatment is a priority in the field of psychiatry. FKBP5 is a gene with decades of evidence suggesting its pathogenic role in a subset of psychiatric patients, with potential to be leveraged as a therapeutic target for these individuals. Whil...

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Detalles Bibliográficos
Autores principales: Matosin, Natalie, Arloth, Janine, Czamara, Darina, Edmond, Katrina Z., Maitra, Malosree, Fröhlich, Anna S., Martinelli, Silvia, Kaul, Dominic, Bartlett, Rachael, Curry, Amber R., Gassen, Nils C., Hafner, Kathrin, Müller, Nikola S., Worf, Karolina, Rehawi, Ghalia, Nagy, Corina, Halldorsdottir, Thorhildur, Cruceanu, Cristiana, Gagliardi, Miriam, Gerstner, Nathalie, Ködel, Maik, Murek, Vanessa, Ziller, Michael J., Scarr, Elizabeth, Tao, Ran, Jaffe, Andrew E., Arzberger, Thomas, Falkai, Peter, Kleinmann, Joel E., Weinberger, Daniel R., Mechawar, Naguib, Schmitt, Andrea, Dean, Brian, Turecki, Gustavo, Hyde, Thomas M., Binder, Elisabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020280/
https://www.ncbi.nlm.nih.gov/pubmed/36729133
http://dx.doi.org/10.1007/s00401-023-02541-9

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