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Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM
Group I introns are catalytic RNAs that coordinate two consecutive transesterification reactions for self-splicing. To understand how the group I intron promotes catalysis and coordinates self-splicing reactions, we determine the structures of L-16 Tetrahymena ribozyme in complex with a 5′-splice si...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020454/ https://www.ncbi.nlm.nih.gov/pubmed/36928031 http://dx.doi.org/10.1038/s41467-023-36724-5 |