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Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride

A reversed-phase RP-HPLC method was developed for the simultaneous determination of metformin hydrochloride (MET), pioglitazone (PIO), and glimepiride (GLM) in their combined dosage forms and spiked human plasma. Quality risk management principles for determining the critical method parameters (CMPs...

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Detalles Bibliográficos
Autores principales: Marie, Aya A., Hammad, Sherin F., Salim, Mohamed M., Elkhodary, Mahmoud M., Kamal, Amira H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020468/
https://www.ncbi.nlm.nih.gov/pubmed/36928591
http://dx.doi.org/10.1038/s41598-023-30051-x