Exosome-mediated inhibition of microRNA-449a promotes the amplification of mouse retinal progenitor cells and enhances their transplantation in retinal degeneration mouse models

Inherited and age-related retinal degenerations are the commonest causes of blindness without effective treatments. Retinal progenitor cells (RPCs), which have the multipotency to differentiate into various retinal cell types, are regarded as a promising source of cell transplantation therapy for re...

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Detalles Bibliográficos
Autores principales: Guo, Chen Jun, Cao, Xiu Li, Zhang, Yu Fei, Yue, Kang Yi, Han, Jing, Yan, Hong, Han, Hua, Zheng, Min Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020531/
https://www.ncbi.nlm.nih.gov/pubmed/36937621
http://dx.doi.org/10.1016/j.omtn.2023.02.015

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