Gaining access to acetyl-CoA by peroxisomal surface display

Synthetic biology is constantly making progress for producing compounds on demand. Recently, Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane. This allowed access to an untapped resource of acetyl-CoA and stimul...

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Detalles Bibliográficos
Autores principales: Perrot, Thomas, Besseau, Sébastien, Papon, Nicolas, Courdavault, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020669/
https://www.ncbi.nlm.nih.gov/pubmed/36936387
http://dx.doi.org/10.1016/j.synbio.2023.02.003
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author Perrot, Thomas
Besseau, Sébastien
Papon, Nicolas
Courdavault, Vincent
author_facet Perrot, Thomas
Besseau, Sébastien
Papon, Nicolas
Courdavault, Vincent
author_sort Perrot, Thomas
collection PubMed
description Synthetic biology is constantly making progress for producing compounds on demand. Recently, Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane. This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide.
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spelling pubmed-100206692023-03-18 Gaining access to acetyl-CoA by peroxisomal surface display Perrot, Thomas Besseau, Sébastien Papon, Nicolas Courdavault, Vincent Synth Syst Biotechnol Article Synthetic biology is constantly making progress for producing compounds on demand. Recently, Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane. This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide. KeAi Publishing 2023-03-06 /pmc/articles/PMC10020669/ /pubmed/36936387 http://dx.doi.org/10.1016/j.synbio.2023.02.003 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Perrot, Thomas
Besseau, Sébastien
Papon, Nicolas
Courdavault, Vincent
Gaining access to acetyl-CoA by peroxisomal surface display
title Gaining access to acetyl-CoA by peroxisomal surface display
title_full Gaining access to acetyl-CoA by peroxisomal surface display
title_fullStr Gaining access to acetyl-CoA by peroxisomal surface display
title_full_unstemmed Gaining access to acetyl-CoA by peroxisomal surface display
title_short Gaining access to acetyl-CoA by peroxisomal surface display
title_sort gaining access to acetyl-coa by peroxisomal surface display
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020669/
https://www.ncbi.nlm.nih.gov/pubmed/36936387
http://dx.doi.org/10.1016/j.synbio.2023.02.003
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AT courdavaultvincent gainingaccesstoacetylcoabyperoxisomalsurfacedisplay

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